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Changes in Membrane Conductance Play a Pathogenic Role in Osmotic Glial Cell Swelling in Detached Retinas

✍ Scribed by Antje Wurm; Thomas Pannicke; Ianors Iandiev; Eva Bühner; Uta-Carolin Pietsch; Andreas Reichenbach; Peter Wiedemann; Susann Uhlmann; Andreas Bringmann


Book ID
117970571
Publisher
American Society for Investigative Pathology
Year
2006
Tongue
English
Weight
943 KB
Volume
169
Category
Article
ISSN
0002-9440

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Glial cell swelling is a central cause of ischemic edema in the brain and retina; however, the regulation of glial cell volume by endogenous factors in situ is largely unknown. In slices of the postischemic retina of the rat, the somata of glial (Müller) cells swell upon hypotonic stress that is not