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Changes in human skin after topical PDT with hexyl aminolevulinate

โœ Scribed by Asta Juzeniene; Kristian Pagh Nielsen; Lu Zhao; Gennady A. Ryzhikov; Marina S. Biryulina; Jakob J. Stamnes; Knut Stamnes; Johan Moan

Book ID
119344286
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
215 KB
Volume
5
Category
Article
ISSN
1572-1000

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In vitro percutaneous absorption and in vivo protoporphyrin IX accumulation in skin and tumors after topical 5-aminolevulinic acid application with enhancement using an erbium:YAG laser
โœ Shing-Chuan Shen; Woan-Ruoh Lee; Yi-Ping Fang; Chung-Hong Hu; Jia-You Fang ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 250 KB

5-Aminolevulinic acid (ALA) is used as a precursor of protoporphyrin IX (PpIX) for photodynamic therapy (PDT) of superficial skin cancers and subcutaneous metastases of internal malignancies. The permeability of ALA across intact skin is always low, making it difficult to achieve the desired therape