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Changes in heregulin β1 (HRGβ1) signaling after inhibition of ErbB-2 expression in a human breast cancer cell line

✍ Scribed by Joo-Yeon Yoo; Anne W Hamburger

Book ID
117463908
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
259 KB
Volume
138
Category
Article
ISSN
0303-7207

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✍ Tracy Lessor; Joo-Yeon Yoo; Myrtle Davis; Anne W. Hamburger 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 121 KB 👁 1 views

The AU565 breast carcinoma cell line was used to determine the role of the extracellular-regulated kinase (ERK) pathway in mediating Heregulin␤1 (HRG␤1)-induced mammary cell differentiation. ERK activation remained elevated for 2 h following high doses of HRG which induce differentiation. In contras