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Changes in dopamine D1, D2and D3receptor mRNA levels in rat brain following antipsychotic treatment

✍ Scribed by Paul R. Buckland; Michael C. O'Donovan; Peter McGuffin

Publisher
Springer
Year
1992
Tongue
English
Weight
512 KB
Volume
106
Category
Article
ISSN
0033-3158

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The purpose of the present study was to assess the role of dopamine D 1 and D 2 receptors in the discriminative stimulus properties of the atypical antipsychotic clozapine (CLZ). Two groups of rats were trained to discriminate either a moderate dose of clozapine (5.0 mg/kg) from vehicle or a high do