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Changes in CSF blood-brain barrier parameters in ischaemic cerebral infarction

✍ Scribed by C. R. Hornig; O. Busse; W. Dorndorf; M. Kaps

Publisher
Springer
Year
1983
Tongue
English
Weight
293 KB
Volume
229
Category
Article
ISSN
0340-5354

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✦ Synopsis

Total CSF protein and CSF/serum albumin and alpha 2-macroglobulin ratios as indicators of a disturbed blood-brain barrier were determined in 39 cases of ischaemic cerebral infarction proved by computed tomography (CT). About 50% of the patients had a barrier disturbance, whereat the CSF serum albumin ratio was shown to be the most sensitive parameter. A disturbed blood-brain barrier was more often found in cases of large infarction, as shown by CT, and occurred most frequently in the first 2 weeks of illness. No correlation was seen between enhancement in CT and disturbance of the blood-brain barrier.

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CSF cyclic AMP and CSF adenylate kinase
CSF cyclic AMP and CSF adenylate kinase in cerebral ischaemic infarction
✍ T. BΓΌttner; C. R. Hornig; O. Busse; W. Dorndorf πŸ“‚ Article πŸ“… 1986 πŸ› Springer 🌐 English βš– 648 KB

The severity of neurological deficits, size of hypodense zone on CT, concentration of cAMP and activity of adenylate kinase in cerebrospinal fluid (CSF) were evaluated at predefined intervals in the acute stage of supratentorial cerebral ischaemic infarction in 52 patients. Patients with cerebral in