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Changes in chondrocyte gene expression following in vitro impaction of porcine articular cartilage in an impact injury model

✍ Scribed by Ashwell, Melissa S.; Gonda, Michael G.; Gray, Kent; Maltecca, Christian; O'Nan, Audrey T.; Cassady, Joseph P.; Mente, Peter L.

Book ID
118763222
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
103 KB
Volume
31
Category
Article
ISSN
0736-0266

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The objective of this study was the development and characterization of an in vitro model of the initiation of traumatic osteoarthritis (OA). Articular cartilage was obtained from seven healthy horses and from four horses diagnosed with OA. Cartilage disks were subjected to a single-impact load (500