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Changes in catecholamine concentrations and synthesis rate in mouse brain during the ‘supersensitivity’ phase after treatment with neuroleptic drugs

✍ Scribed by J. Hyttel; I. Møller Nielsen

Book ID: 111169269
Publisher: John Wiley and Sons
Year: 1976
Tongue: English
Weight: 221 KB
Volume: 27
Category: Article
ISSN: 0022-3042
DOI: 10.1111/j.1471-4159.1976.tb01587.x

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The changes in i4C-dopamine accumulation formed from ~4C-tyrosine in mice after treatment with three neuroleptics, cis (Z)-flupenthixol, fluphenazine, and haloperidol, were followed for 6 days. The neuroleptics all changed DA synthesis rate in the same way, initially causing an increase which was fo