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Changes in brain dopamine receptors in MPTP parkinsonian monkeys followingL-dopa treatment

✍ Scribed by Guillermo M. Alexander; Robert J. Schwartzman; John R. Grothusen; Laine Brainard; Sharon W. Gordon


Book ID
115804165
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
698 KB
Volume
625
Category
Article
ISSN
0006-8993

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The effect of denervation with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) of the dopamine (DA) nigrostriatal pathway on neurotensin (NT) receptor and DA transporter (DAT) in basal ganglia of monkeys (Macaca fascicularis) was investigated. The MPTP lesion induced a marked depletion of DA (90