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Changes in basal and cocaine-evoked extracellular dopamine uptake and release in the rat nucleus accumbens during early abstinence from cocaine: quantitative determination under transient conditions

✍ Scribed by V.I Chefer; T.S Shippenberg

Book ID: 117490483
Publisher: Elsevier Science
Year: 2002
Tongue: English
Weight: 734 KB
Volume: 112
Category: Article
ISSN: 0306-4522
DOI: 10.1016/s0306-4522(02)00099-4

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Rats were treated for 10 days with cocaine (20 mgkg, i.p.1 followed by either 1 or 10 days of abstinence. On the test day a microdialysis method was performed in which dopamine (DA) was added to the perfusate at concentrations above and below the expected extracellular concentration (0,2.5, 5, and 1