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Changes in adenylate cyclase and phosphodiesterase activities during the growth cycle of adult rat hepatocytes in primary culture

✍ Scribed by Pushkaraj J. Lad; Enrique Blazquez; Michael Lin; Hyam L. Leffert


Book ID
115706334
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
507 KB
Volume
232
Category
Article
ISSN
0003-9861

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Serum albumin is the most abundant protein synthesized by liver cells, and its production is a reliable indicator of the differentiated state of hepatocytes. We have recently shown that fetal rat hepatocytes cultured under proliferative conditions, i.e., in the presence of EGF, responded to glucagon