## Background: Although the rate of rna synthesis is known to drop at mitosis, the recent identification of 11 stages in the cell cycle (el-alfy et al., 1994) makes it possible to measure the rate of this synthesis at each one of the stages and thus find out how it varies throughout the cell cycle.
Changes in acid soluble nucleotide components of candida utilis during the cell cycle
โ Scribed by A. N. Hampton; P. S. S. Dawson
- Publisher
- John Wiley and Sons
- Year
- 1969
- Tongue
- English
- Weight
- 403 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0006-3592
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โฆ Synopsis
Acid soluble extracts obtained at 30 min intervals from cells of C. utilis growing in synchrony in a phased culture (cycle time 54 hr) were fractionated on a Dowex-1-formate column. The series of fractionation profiles showed changes in number and amounts of components over the cell cycle. Transient accumulations of numerous components in the complex pool were observed. The significance of the changes are discussed in relation to practical applications and cell metabolism.
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Oxidative phosphorylation within the inner mitochondrial membrane generates the majority of cellular adenosine triphosphate (ATP) required for normal physiological functions (including regulation of cell volume and solute concentration, maintenance of cellular architecture, and synthesis of essentia