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Change Is in the Air: The Hypoxic Induction of Phenotype Switching in Melanoma

✍ Scribed by O'Connell, Michael P; Weeraratna, Ashani T


Book ID
121746437
Publisher
Nature Publishing Group
Year
2013
Tongue
English
Weight
316 KB
Volume
133
Category
Article
ISSN
0022-202X

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## Abstract ## Objective To uncover the mechanism by which hypoxia enhances cartilage matrix synthesis by human articular chondrocytes. ## Methods The hypoxic response was investigated by exposing normal (nonarthritic) human articular chondrocyte cultures to 20% oxygen and 1% oxygen. Induction o