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Change in the connectivity of multidimensional outcomes in a clinical trial of rosiglitazone for Alzheimer's disease

โœ Scribed by Mitnitski, Arnold; Zeng, An; Gold, Michael; Rockwood, Kenneth

Book ID
122354288
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
49 KB
Volume
7
Category
Article
ISSN
1552-5260

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## Abstract ## Background A minimum 4โ€point change at 6 months on the Alzheimer's disease assessment scaleโ€cognitive subscale (ADASโ€cog) is deemed clinically important, but this cutโ€point has been little studied in relation to clinical meaningfulness. In an investigatorโ€initiated, clinical trial o