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Change in rate-limiting step in proton removal from an intramolecularly hydrogen-bonded acid and the rate of opening and closing of a hydrogen bond

✍ Scribed by Briffett, N. E.; Hibbert, Frank; Sellens, R. J.


Book ID
126231050
Publisher
American Chemical Society
Year
1985
Tongue
English
Weight
339 KB
Volume
107
Category
Article
ISSN
0002-7863

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Whenever hydrogen bonding is involved in molecular recognition, the possibility of a proton transfer from the donor to the acceptor arises. In most cases the pK a of the donor is far enough above the pK a of the conjugate acid of the acceptor for it to be clear that no proton transfer will occur. Ho