Change in Oxygen Saturation Does Not Predict Acute Mountain Sickness on Jade Mountain

Spironolactone Does Not Prevent Acute Mo

Spironolactone Does Not Prevent Acute Mountain Sickness: A Prospective, Double-Blind, Randomized, Placebo-Controlled Trial by SPACE Trial Group (Spironolactone and Acetazolamide Trial in the Prevention of Acute Mountain Sickness Group)

✍ Buddha Basnyat; Peter S. Holck; Matiram Pun; Stephen Halverson; Piotr Szawarski; 📂 Article 📅 2011 🏛 Elsevier Science 🌐 English ⚖ 564 KB

## Objectives: Over the last 20 years a number of small trials have reported that spironolactone effectively prevents acute mountain sickness (ams), but to date there have been no large randomized trials investigating the efficacy of spironolactone in prevention of ams. hence, a prospective, double