Change in Chemical Shift and Splitting of 31P γ-ATP Signal in Human Skeletal Muscle During Exercise and Recovery
✍ Scribed by Stefan Widmaier; Wulf-Ingo Jung; Michael Bunse; Franz van Erckelens; Günther Dietze; Otto Lutz
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 777 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0952-3480
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✦ Synopsis
Proton decoupled 31P in vivo NMR spectroscopy of the human finger flexor muscles was performed during exercise and recovery using a 1.5 T whole-body imager. Predominantly the pATP signal shows a splitting caused by different signal contributions with chemical shifts that vary independently. Studies on the human gastrocnemius and biceps femoris muscle were undertaken to investigate the appearance of the splitting in these muscles as well. In all cases more than one signal contribution was found which might represent the different muscle fibre types and their recruitment pattern following exercise. An analysis of the chemical shifts (8) of ATP results in changes of up to 0.4 ppm and 0.1 ppm for Sy-and Sp-ATP, respectively. Based solely on the chemical shifts of the ATP "P signals the tissue pH value following exercise was determined. The result was in good agreement with the value derived from SP,.