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Challenges posed by non-random missing quality of life data in an advanced-stage colorectal cancer clinical trial

✍ Scribed by Carol M. Moinpour; Julia Sawyers Triplett; Barbara McKnight; Laura C. Lovato; Christine Upchurch; Cynthia G. Leichman; Franco M. Muggia; Leora Tanaka; Wendy A. James; Martha Lennard; Frank L. Meyskens Jr

Publisher: John Wiley and Sons
Year: 2000
Tongue: English
Weight: 128 KB
Volume: 9
Category: Article
ISSN: 1057-9249
DOI: 10.1002/1099-1611(200007/08)9:4<340::aid-pon466>3.0.co;2-f

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Measurement of quality of life (QOL) in cancer clinical trials has increased in recent years as more groups realize the importance of such endpoints. A key problem has been missing data. Some QOL data may unavoidably be missing, as for example when patients are too ill to complete forms. Other impor