Challenges for clinical trials on progressive multifocal leukoencephalopathy
โ Scribed by David B. Clifford
- Book ID
- 111739071
- Publisher
- Springer US
- Year
- 2001
- Tongue
- English
- Weight
- 78 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1355-0284
No coin nor oath required. For personal study only.
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## SUMMARY The fatal CNS demyelinating disease, progressive multifocal leukoencephalopathy (PML), is rare and appears to occur almost always as a consequence of immune dysfunction. Thus, it is associated with HIV/AIDS and also as a side effect of certain immunomodulatory monoclonal antibody therapi
pathologically confirmed cases of progressive multifocal leukoencephalopathy (PML) were diagnosed at our institution. Only 1 case had been seen in the preceding twenty years. Four patients had acquired immunodeficiency syndrome (AIDS). The others had chronic lymphocytic leukemia, Hodgkin's lymphoma,