CGP 55845A blocks baclofen, γ-aminobutyric acid and inhibitory postsynaptic potassium currents in guinea pig CA3 neurons

Differences in the Cs block of baclofen

Differences in the Cs block of baclofen and 4-aminopyridine induced potassium currents of guinea pig CA3 neurons in vitro

✍ Wolfgang Jarolimek; Maria Bijak; Ulrich Misgeld 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 920 KB

## Abstract Single‐electrode current‐ and voltage‐clamp techniques were employed to study responses elicited by (−)baclofen or γ‐aminobutyric acid (GABA) and 4‐aminopyridine (4‐AP) induced inhibitory postsynaptic potentials in CA3 pyramidal neurons in guinea pig hippocampal slices. All drugs were a