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CFTR targeting in epithelial cells

โœ Scribed by Andrew P. Morris; Sonia A. Cunningham; Raymond A. Frizzell

Publisher
Springer US
Year
1993
Tongue
English
Weight
808 KB
Volume
25
Category
Article
ISSN
0145-479X

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## Abstract Cystic fibrosis transmembrane conductance regulator (CFTR) is an apical membrane chloride channel critical to the regulation of fluid, chloride, and bicarbonate transport in epithelia and other cell types. The most common cause of cystic fibrosis (CF) is the abnormal trafficking of CFTR