Cetuximab monotherapy in advanced cervical cancer: a retrospective study with five patients
β Scribed by Linda Hertlein; Miriam Lenhard; Angela Kirschenhofer; Steffen Kahlert; Doris Mayr; Alexander Burges; Klaus Friese
- Publisher
- Springer
- Year
- 2010
- Tongue
- English
- Weight
- 148 KB
- Volume
- 283
- Category
- Article
- ISSN
- 0003-9128
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π SIMILAR VOLUMES
## Abstract ## BACKGROUND. Epidermal growth factor receptor (EGFR) and ligand expression is frequently seen in hepatocellular carcinoma (HCC). A phase 2 study was performed with cetuximab, a chimeric monoclonal antibody that binds specifically to EGFR, in patients with advanced HCC. ## METHODS.
A retrospective study was conducted to assess the impact of different clinical parameters on the survival (S), disease free survival (DFS), pelvic recurrence (LR), distant metastases (DM), and the development of major complications in 50 patients with locally advanced cervical cancer. The parameters