Cervical carcinoma and pregnancy: A national patterns of care study of the American College of Surgeons

✍ Scribed by Walter B. Jones; Hugh M. Shingleton; Anthony Russell; Amy M. Fremgen; Rosemarie E. Clive; David P. Winchester; Joan S. Chmiel

• Publisher: John Wiley and Sons
• Year: 1996
• Tongue: English
• Weight: 882 KB
• Volume: 77
• Category: Article
• ISSN: 0008-543X
• DOI: 10.1002/(sici)1097-0142(19960415)77:8<1479::aid-cncr9>3.0.co;2-7

✦ Synopsis

BACKGROUND.

The American College of Surgeons conducted a national patient care and evaluation study of invasive cervical carcinoma in pregnant patients.

METHODS.

Invasive cervical carcinoma was diagnosed in 161 patients who were pregnant at the time of diagnosis. A long term study of 78 patients diagnosed in 1984 was compared with a short term study of 83 patients diagnosed in 1990.

RESULTS.

The mean age of the patients was 31.8 years. Clinical stages were: LA (29%); IB (54%); IIA (6%); IIB (4%); IIIA (0%); IIIB (3%); N (1%; AND IVB (3%). Thirty-one percent of patients were diagnosed in the first trimester, 34% in the second, and 35% in the third. A tumor size of 4 cm or larger in diameter was found in 36% of the patients diagnosed in the first trimester, 40% of the patients diagnosed in the second, and 38% of the patients diagnosed in the third. Patients were treatNed with surgery alone (86), radiotherapy alone (30), or with combination therapy (4ii). The overall 5-year survival rate for patients diagnosed in 1984 was 82%. In this group, the 5-year survival rate for patients diagnosed in the first trimester was 94.6%, in the second, 76.9%, and in the third, 68.9%. Comparing the two time periods, surgical therapy was performed more often by gynecologic oncologists in 1990 (69% vs. 42%), and a greater percentage of patients were diagnosed with a tumor size of 4 cm or larger in diameter (43% vs. 26%) as well as with stage IIB-IVB disease (15% vs. 6.7%).