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Cerebrovascular Effects of Amyloid-ß Peptides: Mechanisms and Implications for Alzheimer's Dementia

✍ Scribed by Costantino Iadecola


Book ID
111547892
Publisher
Springer
Year
2003
Tongue
English
Weight
431 KB
Volume
23
Category
Article
ISSN
0272-4340

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## Abstract The extracellular accumulation of amyloid‐beta (Aβ) in neuritic plaques is one of the characteristic hallmarks of Alzheimer's disease (AD), a progressive dementing neurodegenerative disorder of the elderly. By virtue of its structure, Aβ is able to bind to a variety of biomolecules, inc