Cerebrospinal fluid plasminogen activator inhibitor-1: a prognostic factor in posthaemorrhagic hydrocephalus
✍ Scribed by A Hansen; A Whitelaw; C Lapp; C Brugnara
- Book ID
- 114811420
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 411 KB
- Volume
- 86
- Category
- Article
- ISSN
- 0803-5253
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The occurrence of type-1 plasminogen activator inhibitor (PAI-1) in human cerebrospinal fluid (CSF) has not previously been reported. As a member of the serpin superfamily of serine protease inhibitors and an acute phase response component, PAI-1 has powerful potential roles in nervous system homeos
## Abstract ## Background. Tumor cell biological factors, such as urokinase plasminogen activator (uPA) and its inhibitor plasminogen activator inhibitor‐1 (PAI‐1), cathepsin D, and c‐myc play a role in tumor invasion, metastasis, and proliferation. In this study, the prognostic importance of thes