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Cerebral metabolic changes induced by clozapine in schizophrenia and related to clinical improvement

✍ Scribed by Vicente Molina; Juan D. Gispert; Santiago Reig; Javier Sanz; Javier Pascau; Andrés Santos; Manuel Desco; Tomás Palomo

Publisher
Springer
Year
2004
Tongue
English
Weight
538 KB
Volume
178
Category
Article
ISSN
0033-3158

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Reactive oxygen metabolites (ROM), produced by mononuclear phagocytes may participate in brain pathology. Clozapine (CLO) may modulate cell immunity, and it is also superior to conventional neuroleptics in conditions with a putative impact of oxidative damage by ROM, i.e. negative symptoms and neuro