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Cerebral ischemia and neuroprotective action of GM1 ganglioside: Relationship with anti-excitotoxic effects

✍ Scribed by Leon, A.; Lipartiti, M.; Seren, M.S.; Lazzaro, A.; Mazzari, S.; Toffano, G.

Book ID: 123247585
Publisher: Elsevier Science
Year: 1990
Tongue: English
Weight: 73 KB
Volume: 22
Category: Article
ISSN: 1043-6618
DOI: 10.1016/S1043-6618(09)80292-2

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## Abstract We have previously reported that prostaglandin A~1~ (PGA~1~) reduces infarct size in rodent models of focal ischemia. This study seeks to elucidate the possible molecular mechanisms underlying PGA~1~'s neuroprotective effects against ischemic injury. Rats were subjected to permanent mid