CEREBRAL CHANGES IN OLD AGE DEPRESSION: A CASE REPORT WITH FINDINGS ON SINGLE PHOTON EMISSION TOMOGRAPHY
✍ Scribed by AJAY UPADHYAYA; M. T. ABOU-SALEH; S. GRIME; M. N. SATISH
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 384 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0885-6230
No coin nor oath required. For personal study only.
✦ Synopsis
An 82-year-old woman with no past psychiatric history developed a depressive illness from which she recovered within 2 months of initiating antidepressant therapy. She underwent single photon emission computerized tomography (SPET) when depressed and subsequently 3 and 8 months after complete clinical recovery. Impaired cerebral perfusion evident during the depressed phase improved with clinical recovery, suggesting that the impaired perfusion accompanying the depressed state is partly a state dependent abnormality. However, the possibility of persistence of such impairment beyond clinical recovery cannot be ruled out.