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Cerebral blood flow and BOLD fMRI responses to hypoxia in awake and anesthetized rats

✍ Scribed by Timothy Q. Duong

Book ID
113502447
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
669 KB
Volume
1135
Category
Article
ISSN
0006-8993

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To decipher the biophysical mechanism behind the fMRI-BOLD response to apnea and its dependence on the baseline cerebral blood flow and oxygenation, fMRI and laser Doppler flow (LDF) studies were carried out in anesthetized rats. Baseline cerebral blood flow (CBF) and P a O 2 were modulated by venti