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Cerebellar Transplants into Mutant Mice with Purkinje and Granule Cell Degeneration

✍ Scribed by WALTER C. LOW; LAZAROS C. TRIARHOU; BERNARDINO GHETTI


Book ID
119859180
Publisher
John Wiley and Sons
Year
1987
Tongue
English
Weight
437 KB
Volume
495
Category
Article
ISSN
0890-6564

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Effect of purkinje cell loss on cerebell
✍ Dr. T. N. Seyfried; D. J. Bernard; R. K. Yu πŸ“‚ Article πŸ“… 1987 πŸ› John Wiley and Sons 🌐 English βš– 483 KB

The distribution of cerebellar gangliosides was studied in adult (73 +/- 2 days) nervous (nr/nr) mutant mice which lose 50-90% of their Purkinje cells. This neuronal loss is associated with significant reductions in cerebellar weight and ganglioside concentration. The cerebellar dry weights (mg) and