Cerebellar ataxia and gluten sensitivity: a rare but possible cause of ataxia, even in childhood

POLG, but not PEO1, is a frequent cause

POLG, but not PEO1, is a frequent cause of cerebellar ataxia in Central Europe

✍ Julia Schicks; Matthis Synofzik; Claudia Schulte; Ludger Schöls 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 645 KB

## Abstract Nuclear genes, in particular mitochondrial polymerase gamma (__POLG__) and __PEO1__, have been increasingly recognized to cause mitochondrial diseases. Both genes assume a complementary role as part of the mitochondrial DNA (mtDNA) replication fork and, accordingly, seem to present with