Escape mechanisms of human leukemic cell
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Roberto Chignola; Marcella Pasti; Carola Candiani; Antonia Franceschi; Cristina
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Article
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1995
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John Wiley and Sons
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French
⚖ 830 KB
## Abstract In kinetic assays, an anti‐CD5‐ricin A chain (ST.1 ‐RTA) immunoconjugate (immunotoxins, IT) specifically inhibited up to 40% the protein synthesis of Jurkat target cells within the first 40 hr. Longer exposures of leukemia cells to ST.I‐RTA resulted in a progressively higher number of t