Advanced glycation end-products activate
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San-Cher Chen; Jinn-Yuh Guh; Chi-Ching Hwang; Shean-Jaw Chiou; Tai-Du Lin; Yu-Mi
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Article
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2009
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John Wiley and Sons
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English
⚖ 366 KB
## Abstract Advanced glycation end‐products (AGEs), epidermal growth factor receptor (EGFR), reactive oxygen species (ROS), and extracellular signal‐regulated kinases (ERK) are implicated in diabetic nephropathy (DN). Therefore, we asked if AGEs‐induced ERK protein phosphorylation and mitogenesis a