𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Cepstral estimation of arterial input functions in brain perfusion imaging

✍ Scribed by Renate Grüner; Torfinn Taxt

Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
882 KB
Volume
26
Category
Article
ISSN
1053-1807

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Purpose

To investigate voxel‐specific arterial input functions (AIFs) obtained through blind deconvolution using complex cepstrum liftering. Blindly estimated AIFs have the potential of reducing dispersion effects in perfusion maps and are completely user‐independent.

Materials and Methods

The separability of AIFs and tissue residue functions (TRFs) in the cepstrum domain is exemplified using synthetic data, wherein the AIFs are modeled as gamma variate functions and the TRFs are modeled as exponential or linear functions. A novel separation filter is suggested. Initial results of different blind methods are illustrated using data from a stroke patient.

Results

The AIFs and the TRFs partly overlap in the complex cepstrum. The AIFs, obtained using the new separation filter, are closer to those obtained using noncepstral blind separation.

Conclusion

The overlap of AIFs and TRFs in the complex cepstrum makes reliable separation of the two functions more difficult than previously described. Comparison to noncepstral blind methods suggests that similar optima are found using the new separation filter. J. Magn. Reson. Imaging 2007;26:773–779. © 2007 Wiley‐Liss, Inc.

📜 SIMILAR VOLUMES

Magnetic resonance brain perfusion imagi
Magnetic resonance brain perfusion imaging with voxel-specific arterial input functions
✍ Renate Grüner; Bård T. Bjørnarå; Gunnar Moen; Torfinn Taxt 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 851 KB

## Abstract ## Purpose To propose an automatic method for estimating voxel‐specific arterial input functions (AIFs) in dynamic contrast brain perfusion imaging. ## Materials and Methods Voxel‐specific AIFs were estimated blindly using the theory of homomorphic transformations and complex cepstru

Implementation of quantitative perfusion
Implementation of quantitative perfusion imaging techniques for functional brain mapping using pulsed arterial spin labeling
✍ Eric C. Wong; Richard B. Buxton; Lawrence R. Frank 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 626 KB

We describe here experimental considerations in the implementation of quantitative perfusion imaging techniques for functional MRI using pulsed arterial spin labeling. Three tagging techniques: EPISTAR, PICORE, and FAIR are found to give very similar perfusion results despite large differences in st

Separating function from structure in pe
Separating function from structure in perfusion imaging of the aging brain
✍ Iris Asllani; Christian Habeck; Ajna Borogovac; Truman R. Brown; Adam M. Brickma 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 388 KB 👁 1 views

## Abstract The accuracy of cerebral blood flow (CBF) imaging in humans has been impeded by the partial volume effects (PVE), which are a consequence of the limited spatial resolution. Because of brain atrophy, PVE can be particularly problematic in imaging the elderly and can considerably overesti

Scan-rescan variability in perfusion ass
Scan-rescan variability in perfusion assessment of tumors in MRI using both model and data-derived arterial input functions
✍ Edward Ashton; David Raunig; Chaan Ng; Fredrick Kelcz; Teresa McShane; Jeffrey E 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 402 KB

## Abstract ## Purpose To evaluate the contribution to scan‐rescan coefficient of variation (CV) of patient‐specific arterial input function (AIF) measurement in dynamic contrast‐enhanced MRI (DCE‐MRI) data, and to determine whether any advantage or disadvantage to using a data‐derived arterial in