Cephalosol: An Antimicrobial Metabolite with an Unprecedented Skeleton from Endophytic Cephalosporium acremonium IFB-E007

✍ Scribed by Hua Wei Zhang; Wu Yang Huang; Jing Rong Chen; Wei Zhong Yan; Dai Qian Xie; Ren Xiang Tan

• Publisher: John Wiley and Sons
• Year: 2008
• Tongue: English
• Weight: 206 KB
• Volume: 14
• Category: Article
• ISSN: 0947-6539
• DOI: 10.1002/chem.200801000

✦ Synopsis

Abstract

Cephalosol (1), a potent antimicrobial secondary metabolite with a new carbon skeleton, was characterized from the culture of Cephalosporium acremonium IFB‐E007 that used to reside as an endophyte in Trachelospermum jasminoides (Apocynaceae). Its structure and absolute configuration were unambiguously determined by spectroscopic and computational approaches.