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Centrosome overduplication and mitotic instability in PKD2 transgenic lines

✍ Scribed by Stéphane Burtey; Marta Riera; Émilie Ribe; Petra Pennenkamp; Roselyne Rance; Judith Luciani; Bernd Dworniczak; Marie Geneviève Mattei; Michel Fontés


Book ID
108084656
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
342 KB
Volume
32
Category
Article
ISSN
1065-6995

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Measurement of the nuclear DNA content allows classification of human cancers as either diploid or aneuploid. To gain further insight into mechanisms of aneuploidy, we compared the cytogenetic profile of mismatch-repair-deficient diploid versus mismatch-repair-proficient aneuploid colorectal carcino