Centrosome Amplification and the Origin of Chromosomal Instability in Breast Cancer
โ Scribed by Jeffrey L. Salisbury; Antonino B. D'Assoro; Wilma L. Lingle
- Book ID
- 111593739
- Publisher
- Springer US
- Year
- 2004
- Tongue
- English
- Weight
- 210 KB
- Volume
- 9
- Category
- Article
- ISSN
- 1083-3021
No coin nor oath required. For personal study only.
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Over-expression of a centrosomal serine/threonine kinase, STK15/BTAK, induces centrosome amplification, which results in chromosomal instability (CIN) in cell culture. In the present study, we investigated the correlation of STK15/BTAK mRNA expression with CIN and various clinicopathological factors