✦ LIBER ✦

Centrosome aberrations in chronic myeloid leukemia correlate with stage of disease and chromosomal instability

✍ Scribed by Giehl, M; Fabarius, A; Frank, O; Hochhaus, A; Hafner, M; Hehlmann, R; Seifarth, W

Book ID: 110056301
Publisher: Nature Publishing Group
Year: 2005
Tongue: English
Weight: 145 KB
Volume: 19
Category: Article
ISSN: 0887-6924
DOI: 10.1038/sj.leu.2403779

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Gene expression patterns in acute myeloi

Gene expression patterns in acute myeloid leukemia correlate with centrosome aberrations and numerical chromosome changes

✍ Neben, Kai; Tews, Björn; Wrobel, Gunnar; Hahn, Meinhard; Kokocinski, Felix; Gies 📂 Article 📅 2004 🏛 Nature Publishing Group 🌐 English ⚖ 314 KB

The presence of high-risk chromosome abe

The presence of high-risk chromosome aberrations in chronic lymphocytic leukaemia does not correlate with centrosome aberrations

✍ Laura Ottaggio; Annalisa Zunino; Irena Maric; Alessia Grozio; Edoardo Rossi; Mau 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 99 KB 👁 1 views

## Abstract Chromosome aberrations are frequently found in B‐cell chronic lymphocytic leukaemia (B‐CLL), and specific chromosome aberrations identify poor prognostic subgroups. Almost all the aberrations identified in B‐CLL involve loci where genes with a role in the regulation of centrosome duplic

Occurrence of additional chromosome aber

Occurrence of additional chromosome aberrations in chronic myeloid leukemia patients treated with imatinib mesylate

✍ Schoch, C; Haferlach, T; Kern, W; Schnittger, S; Berger, U; Hehlmann, R; Hiddema 📂 Article 📅 2003 🏛 Nature Publishing Group 🌐 English ⚖ 112 KB

High rate of centrosome aberrations and

High rate of centrosome aberrations and correlation with proliferative activity in patients with untreated B-cell chronic lymphocytic leukemia

✍ Manfred Hensel; Martin Zoz; Christian Giesecke; Axel Benner; Kai Neben; Anna Jau 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 French ⚖ 138 KB 👁 1 views

## Abstract B‐cell chronic lymphocytic leukemia (CLL) is characterized by a high rate of clonal genomic alterations and a low proliferative activity with cell cycle arrest in G~0~/G~1~ phase. Recently, centrosome aberrations have been described as a possible cause of chromosomal instability and ane

Centrosome amplification and instability

Centrosome amplification and instability occurs exclusively in aneuploid, but not in diploid colorectal cancer cell lines, and correlates with numerical chromosomal aberrations

✍ B. Michael Ghadimi; Dan L. Sackett; Michael J. Difilippantonio; Evelin Schröck; 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 578 KB

Measurement of the nuclear DNA content allows classification of human cancers as either diploid or aneuploid. To gain further insight into mechanisms of aneuploidy, we compared the cytogenetic profile of mismatch-repair-deficient diploid versus mismatch-repair-proficient aneuploid colorectal carcino

The amount of BCR-ABL fusion transcripts

The amount of BCR-ABL fusion transcripts detected by the real-time quantitative polymerase chain reaction method in patients with Philadelphia chromosome positive chronic myeloid leukemia correlates with the disease stage

✍ A. H. Elmaagacli; D. W. Beelen; B. Opalka; S. Seeber; U. W. Schaefer 📂 Article 📅 2000 🏛 Springer 🌐 English ⚖ 149 KB