Centronuclear myopathy: Extraocular- and limb-muscle findings in an adult

✍ Scribed by Dr. Barry J. Bergen; Dr. Michael P. Carry; Dr. W. Bruce Wilson; Mr. Michael T. Barden; Dr. Steven P. Ringel

• Book ID: 102954891
• Publisher: John Wiley and Sons
• Year: 1980
• Tongue: English
• Weight: 907 KB
• Volume: 3
• Category: Article
• ISSN: 0148-639X
• DOI: 10.1002/mus.880030210

✦ Synopsis

Abstract

Myotube‐like structures were seen in extraocular and limb muscles in an adult with centronuclear myopathy. The limb‐muscle fibers were very small and were of a uniform histochemical type. Extrajunctional acetylcholine receptors were not seen with immunoperoxidase stains, and ultrastructurally normal neuromuscular junctions were seen in the extraocular‐muscle samples. Further studies on developing muscle are needed to identify possible mechanisms of arrest of muscle maturation.