✦ LIBER ✦
Centromere inactivation in a case of turner variant with two dicentric iso-long arm Y chromosomes
✍ Scribed by W. Schmid; V. D'Apuzzo
- Publisher
- Springer
- Year
- 1978
- Tongue
- English
- Weight
- 294 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0340-6717
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✦ Synopsis
A 6-year-old girl of small stature and with some features of Turner's syndrome was found to have a karyotype with two-thirds of the cells possessing one, and one-third with two dicentric iso-long arm Y chromosomes. In metaphases with 46 chromosomes the majority of the abnormal Ys exhibited two primary constrictions. In cells with 47 chromosomes both isochromosomes prevalently had only one active centromere.