Lovastatin (LOV), a hydroxy-methylglutaryl-coenzyme A (HMGCoA) reductase competitive inhibitor, blocks epidermal growth factor (EGF)or prostaglandin F , , (PGF,,)-induced mitogenesis in confluent resting Swiss 3T3 cells. This inhibition occurs even in the presence of insulin, which potentiates the a
Centriole deciliation associated with the early response of 3T3 cells to growth factors but not to SV40
โ Scribed by Tucker, R.W.; Scher, C.D.; Stiles, C.D.
- Book ID
- 122504069
- Publisher
- Elsevier Science
- Year
- 1979
- Tongue
- English
- Weight
- 775 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0092-8674
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