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Central tolerance: Essential for preventing autoimmune disease?

✍ Scribed by Harald von Boehmer

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
100 KB
Volume
39
Category
Article
ISSN
0014-2980

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## Abstract Autoimmune diseases are characterized by the loss of tolerance toward self‐antigens and the induction of destructive immune responses leading to tissue damage. Most patients with autoimmune diseases are treated with immunosuppressive drugs that suppress the immune response in a non‐spec