The clinical science of migraine headache continues to evolve. Theories of the pathophysiology of migraine have progressed from the early vascular basis of migraine to more complex current theories that emphasize the centrality of neuronal dysfunction. The most recently articulated theory of migrain
โฆ LIBER โฆ
Central Sensitization Theory of Migraine: Clinical Implications
โ Scribed by David Dodick; Stephen Silberstein
- Book ID
- 109099771
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 146 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0017-8748
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Nociceptor inputs can trigger a prolonged but reversible increase in the excitability and synaptic efficacy of neurons in central nociceptive pathways, the phenomenon of central sensitization. Central sensitization manifests as pain hypersensitivity, particularly dynamic tactile allodynia, secondary