Central precocious puberty in Klinefelter syndrome: A case report with longitudinal follow-up of growth pattern
✍ Scribed by Bertelloni, Silvano; Baroncelli, Giampiero I.; Battini, Roberta; Saggese, Giuseppe
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 428 KB
- Volume
- 65
- Category
- Article
- ISSN
- 0148-7299
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✦ Synopsis
We report idiopathic central precocious puberty in a boy with Klinefelter syndrome and describe the pattern of linear growth and body proportion from the onset of precocious puberty to final height. The patient was not treated for precocious puberty. He reached adequate adult height, for both general population and normative values of Klinefelter syndrome and normal body proportions. We conclude that precocious puberty in Klinefelter syndrome may result in normal body proportion by inducing a major growth spurt of the trunk rather than in the limbs, and that adult height prognosis is not altered by precocious puberty. Given the possible occurrence of precocious puberty in Klinefelter syndrome, we advise a karyotype analysis in boys with sexual precocity, mainly in those who show small rather than enlarged testes.