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Central nervous system toxicity of high-dose systemic cytosine arabinoside

✍ Scribed by Hillard M. Lazarus; Roger H. Herzig; David J. Fishman; Geoffrey P. Herzig; Gordon L. Phillips; Uros Roessmann


Publisher
John Wiley and Sons
Year
1981
Tongue
English
Weight
624 KB
Volume
48
Category
Article
ISSN
0008-543X

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Background. Given the good penetration of systemic high-dose cytarabine (HDara-C) into the cerebrospinal fluid (CSF), this approach was used to treat patients with central nervous system (CNS) leukemia, either isolated or with concurrent extraneurologic disease (END). Methods. From 1983 to 1991,46