Central nervous system involvement in infectious mononucleosis with studies for Epstein-Barr virus
✍ Scribed by M. Duniewicz; J. Lasovská; K. Kouba; J. Railichová; J. Baierová; H. Karpenková; K. Vojtěchovský
- Publisher
- Springer-Verlag
- Year
- 1976
- Tongue
- English
- Weight
- 368 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0300-8126
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## Abstract The presence of Epstein‐Barr virus (EBV) in the blood and urine of 20 patients with infectious mononucleosis (IM) was investigated together with the clinical course of the disease, and in 9 patients up to 2–7 months after recovery. EBV DNA, analyzed by the polymerase chain reaction (PCR
Epstein-Barr virus infection can affect both the central and peripheral nervous system. In some patients this occurs concurrently. Two patients are presented with encephalopathy and acute quadriparesis with diminished reflexes. Positive serology for Epstein-Barr virus was found in both patients. Bot
Acute Epstein-Barr virus (EBV) infection of the central nervous system (CNS) is associated with meningoencephalitis and other neurological syndromes and with CNS lymphomas (CNSLs). Diagnosis is based on serological studies and more recently on detection of EBV DNA in cerebrospinal fluid (CSF) by pol