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Central Nervous System Expression of Interferon Regulatory Factor 1 Regulates Experimental Autoimmune Encephalomyelitis

✍ Scribed by Ren, Zhihua; Wang, Yan; Tao, Duan; Liebenson, David; Liggett, Thomas; Goswami, Rajendra; Stefoski, Dusan; Balabanov, Roumen

Book ID: 107380725
Publisher: Springer US
Year: 2010
Tongue: English
Weight: 418 KB
Volume: 5
Category: Article
ISSN: 1557-1890
DOI: 10.1007/s11481-010-9193-z

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## Abstract Experimental autoimmune encephalomyelitis (EAE) is a CD4^+^ T cell disease of the central nervous system (CNS) characterized by mononuclear cell infiltration, demyelination, and paralysis. Recent studies describing the relationship of chemokine expression with development of clinical di