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Central Nervous System Blast Crisis in Chronic Myeloid Leukemia on Imatinib Mesylate Therapy: Report of Two Cases

✍ Scribed by Narayan Radhika; Mishra Minakshi; Mohanty Rajesh; Baisakh R. Manas; Mishra Deepak Kumar


Publisher
Springer-Verlag
Year
2011
Tongue
English
Weight
214 KB
Volume
27
Category
Article
ISSN
0971-4502

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Imatinib mesylate (IM) therapy leads to a complete cytogenetic response (CCyR) in 75-90% of Chronic Myeloid Leukemia (CML) patients in chronic phase, but only a small percentage of patients achieve complete molecular response (CMR). Very little is known about IM discontinuation. We report the case o