Central involvement of Rho family GTPases in TNF-α-mediated bovine pulmonary endothelial cell apoptosis

Mast cell-mediated apoptosis of endothel

Mast cell-mediated apoptosis of endothelial cells in vitro: A paracrine mechanism involving TNF-α-mediated down-regulation of bcl-2 expression

✍ Soili Lätti; Markus Leskinen; Naotaka Shiota; Yenfeng Wang; Petri T. Kovanen; Ke 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 302 KB 👁 1 views

## Abstract Degranulated mast cells are present in the subendothelial space of eroded (de‐endothelialized) coronary atheromas. Upon degranulation, mast cells secrete into the surrounding tissue an array of preformed and newly synthesized mediators, including proapoptotic molecules, such as chymase