Central effects of drugs used in migraine prophylaxis evaluated by visual evoked potentials

Structural features of a central mismatc

Structural features of a central mismatch in oligonucleotide hybrid duplexes visualized via Raman spectroscopy: Model system for evaluation of potential “antisense” drugs

✍ Daniel Nĕmec̆ek; Hana Vaisocherová; Josef S̆tĕpánek; Pierre-Yves Turpin 📂 Article 📅 2005 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 378 KB 👁 2 views

## Abstract Structural features of mismatched base pairs were studied on four nonamer hybrid duplexes formed between the 5′‐d(GTGATATGC)‐3′ complement and its 5′‐r(GCAU__N__UCAC)‐3′ (__N__ = A, C, G, U) counterparts. This oligonucleotide set is considered a model molecular system for future systema