𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Central cholinergic activity in aluminum-induced neurofibrillary degeneration

✍ Scribed by Bogumil Hetnarski; Dr. Henryk M. Wisniewski; Khalid Iqbal; John D. Dziedzic; Abel Lajtha

Publisher
John Wiley and Sons
Year
1980
Tongue
English
Weight
191 KB
Volume
7
Category
Article
ISSN
0364-5134

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Choline acetyltransferase (CAT) and acetylcholinesterase (AChE) activities were measured in spinal cord homogenates from rabbits with aluminum‐induced neurofibrillary degeneration and a group of salinetreated, age‐matched controls. All Aluminum ‐treated animals showed neurofibrillary changes in the spinal cord, but CAT and AChE activities were not significantly different from levels in control animals. These results are at variance with the greatly reduced activity of these enzymes observed in Alzheimer disease and senile dementia of the Alzheimer type.

πŸ“œ SIMILAR VOLUMES

Naltrexone pretreatment blocks microwave
Naltrexone pretreatment blocks microwave-induced changes in central cholinergic receptors
✍ H. Lai; M. A. Carino; Y. F. Wen; A. Horita; A. W. Guy πŸ“‚ Article πŸ“… 1991 πŸ› John Wiley and Sons 🌐 English βš– 413 KB

Repeated exposure of rats to pulsed, circularly polarized microwaves (2,450-MHq 2 -p ~ pulses at 500 pps, power density 1 mW/cm2, at an averaged, whole-body SAR of 0.6 W/kg) induced biphasic changes in the concentration of muscarinic cholinergic receptors in the central nervous system. An increase i